Unraveling the Complexities of T wave Alternans and QT Prolongation in Advanced Chronic Kidney Disease: A Case Report and Literature Review

Authors

  • Rana Mohamed Department of Medicine, King Abdulaziz Hospital, Ministry of National Guard Health Affairs -AlAhsa, Saudi Arabia
  • Ahmad Almuhanna Department of Medicine, King Abdulaziz Hospital, Ministry of National Guard Health Affairs -AlAhsa, Saudi Arabia
  • Hawra Alajwad Department of Medicine, King Fahad Hospital, Ministry of Health - Al Ahsa, Saudi Arabia
  • Amin Elshehawey Department of Medicine, King Abdulaziz Hospital, Ministry of National Guard Health Affairs -AlAhsa, Saudi Arabia
  • Abdulmohsen Almusaad King Abdullah International Medical Research Center (KAIMRC), Al Ahsa, Saudi Arabia & King Abdulaziz Cardiac Center, King Abdulaziz Medical City, Ministry of National Guard Health Affairs -Riyadh, Saudi Arabia 
  • Muneera AlTaweel Department of Medicine, King Abdulaziz Hospital, Ministry of National Guard Health Affairs -AlAhsa, Saudi Arabia & King Abdullah International Medical Research Center (KAIMRC), Al Ahsa, Saudi Arabia

DOI:

https://doi.org/10.55677/IJCSMR/V4I6-05/2024

Keywords:

T-wave alternans, QT prolongation, chronic kidney disease, ventricular arrhythmias, sudden cardiac death, electrolyte imbalance, hemodialysis.

Abstract

The recognition of QT interval prolongation and T-wave alternans (TWA) on an electrocardiogram (ECG) is a critical prognostic criterion. We report a 78-year-old patient with advanced chronic kidney disease (CKD) to demonstrate the intricate interaction of variables leading to electrical instability in this demographic, in addition to stressing the relevance of comprehensive diagnostic and therapeutic techniques. We underline the significance of TWA and QT prolongation as indicators for imminent ventricular arrhythmias and sudden cardiac death (SCD). The case underscores the multifactorial causes of QT prolongation and TWA in CKD. It highlights the need for further research to understand the underlying mechanisms better and develop strategies to mitigate risks in CKD patients.

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Published

2024-06-22

How to Cite

Mohamed, R., Almuhanna, A., Alajwad, H., Elshehawey, A., Almusaad, A., & AlTaweel, M. (2024). Unraveling the Complexities of T wave Alternans and QT Prolongation in Advanced Chronic Kidney Disease: A Case Report and Literature Review. International Journal of Clinical Science and Medical Research, 4(6), 209–218. https://doi.org/10.55677/IJCSMR/V4I6-05/2024

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Vol. 4 No. 6 (2024): Volume 04 Issue 06 June 2024

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