Impact of Early Diagnosis and Intravenous Immunoglobulin on the Health-Related Quality of Life of Primary Immune Deficiency Children
DOI:
https://doi.org/10.55677/IJCSMR/V3I10-02/2023Keywords:
PID, IEI, QOL, HRQOL of children.Abstract
Background: Inborn errors of immunity (IEI) are rare hereditary genetic, with around 485 rare immune system defects. Health-Related Quality of life (HRQOL) of children and adolescents with IEI is influenced by the early diagnosis of the disease, Immunoglobulin replacement, type of IEI, socio-economic status, family, social support, medical et social environment. Little attention is given to the HRQOL of patients, health professionals and stakeholders tend to focus on medical treatment more than the other aspect of the quality of life. The objective of this study is to measure the improvement of the HRQOL after the diagnosis and the Immunoglobin treatment of IEI patients in Morocco.
Results: Total HRQOL was improved after diagnosis and treatment administration (Ig therapy) for the two groups of IEI patients using the generic EQ-5D-Y instrument (p = 0.0009). The improvement was most significant in the physical domain, financial, and schooling domains using the KIDSCREEN-52 instrument.
Conclusions: Health-Related Quality of Life plays a major role in health care; it gives insights into the factors that may improve the provision of health services.
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