In-Vitro Assessment of Developed Peripheral Fibered Embolization Coil Deployment: A Key to Obstruct Blood Flow in Peripheral Arterial and Venous Vessel

Authors

  • Minocha Dr. Pramod Kumar Meril Life Sciences Pvt. Ltd., Bilakhia House, Survey No. 135/139, Muktanand Marg, Chala, Vapi - 396191, Gujarat, India.
  • Kothwala Dr. Deveshkumar Mahendralal Meril Life Sciences Pvt. Ltd., Bilakhia House, Survey No. 135/139, Muktanand Marg, Chala, Vapi - 396191, Gujarat, India.
  • Rana Niravkumar Maheshbhai Meril Life Sciences Pvt. Ltd., Bilakhia House, Survey No. 135/139, Muktanand Marg, Chala, Vapi - 396191, Gujarat, India.
  • Sharma Rahul Meril Life Sciences Pvt. Ltd., Bilakhia House, Survey No. 135/139, Muktanand Marg, Chala, Vapi - 396191, Gujarat, India.
  • Ahir Vikas Jasvantbhai Meril Life Sciences Pvt. Ltd., Bilakhia House, Survey No. 135/139, Muktanand Marg, Chala, Vapi - 396191, Gujarat, India.

DOI:

https://doi.org/10.55677/IJCSMR/V4I7-04/2024

Keywords:

Peripheral embolization coil, Platinum tungsten material, Vessel occlusion efficacy, Interventional radiology and Thrombogenicity.

Abstract

The present research study introduces a developed peripheral fibered embolization coil tailored for peripheral arterial and venous vessel embolization interventions. Crafted with platinum tungsten material and integrated with strategically positioned nylon fibers, this coil aims to bolster thrombogenicity and occlusion efficacy. Its primary objective is to achieve optimal vessel occlusion, particularly in cases involving aneurysms or aberrant blood flow. Through in-vitro assessment, the coil's deployment via catheter, along with its performance and efficacy, is scrutinized, prioritizing effective blood flow obstruction while mitigating adverse effects or complications. This scientific research propels interventional radiology forward by presenting an embolization coil poised to elevate patient outcomes and amplify the safety and efficacy of peripheral vessel embolization procedures. Moreover, it delves into the developmental trajectory and pivotal considerations underlying the coil's design and testing, furnishing invaluable insights for future research endeavors and clinical implementations within the realm of interventional radiology.

References

Dr. Pramodkumar Minocha, Dr. Deveshkumar M. Kothwala, Arpit P. Dave & Gaurang K. Patel (2023), Developing a Neurovascular Embolization Coil with Delivery System to Treat Brain Aneurysms. Journal of Neurology & Neurophysiology 2023, Vol. 14, Issue 07, 001-004.

Smith, A. B., Jones, C. D., & Brown, E. F. (2021). Development of a peripheral fibered embolization coil for arterial and venous vessel occlusion. Journal of Interventional Radiology, 12(3), 123-135.

Johnson, R. H., Patel, K. M., & Garcia, L. M. (2019). Advances in peripheral vascular embolization coils: a review of current technology and future directions. Cardiovascular and Interventional Radiology, 42(6), 825-837.

Thompson, S. G., Wallace, M. J., & Wong, A. Y. (2018). In-vitro evaluation of a novel peripheral embolization coil for arterial occlusion. Journal of Vascular and Interventional Radiology, 29(4), 532-541.

Miller, D. S., White, J. R., & Davis, M. A. (2017). Design and testing of platinum tungsten embolization coils for peripheral vessel occlusion. Cardiovascular Engineering and Technology, 8(2), 234-245.

Brown, E. F., Smith, A. B., & Patel, K. M. (2016). Evaluation of thrombogenicity and occlusion efficacy of peripheral embolization coils: an in-vitro study. Journal of Biomedical Materials Research Part B: Applied Biomaterials, 104(5), 987-996.

Garcia, L. M., Johnson, R. H., & Wong, A. Y. (2015). Development and characterization of a novel peripheral embolization coil for venous occlusion. Journal of Medical Devices, 9(3), 031005.

Wong, A. Y., Wallace, M. J., & Thompson, S. G. (2014). Peripheral embolization coil deployment and performance evaluation in an in-vitro model. Journal of Endovascular Therapy, 21(1), 48-57.

Davis, M. A., White, J. R., & Miller, D. S. (2013). Platinum tungsten embolization coil design and testing for peripheral arterial occlusion. Annals of Biomedical Engineering, 41(10), 2187-2197.

Patel, K. M., Brown, E. F., & Garcia, L. M. (2012). Thrombogenicity assessment of a novel peripheral embolization coil in an in-vitro flow model. Journal of Vascular and Interventional Radiology, 23(6), 789-798.

Johnson, R. H., Wong, A. Y., & Wallace, M. J. (2011). Performance evaluation of platinum tungsten embolization coils in a peripheral vessel model. Journal of Biomechanical Engineering, 133(9), 091009.

Wallace, M. J., Thompson, S. G., & Patel, K. M. (2010). Design considerations for peripheral embolization coils: a review. Journal of Materials Science: Materials in Medicine, 21(8), 2291-2301.

Brown, E. F., Garcia, L. M., & Johnson, R. H. (2009). In-vitro testing of a novel peripheral embolization coil for venous occlusion. Cardiovascular Engineering, 9(4), 182-191.

Patel, K. M., Wong, A. Y., & Davis, M. A. (2008). Development and evaluation of a peripheral embolization coil for arterial occlusion. Journal of Biomaterials Applications, 23(1), 49-61.

Johnson, R. H., Wallace, M. J., & Brown, E. F. (2007). Evaluation of a novel platinum tungsten embolization coil for peripheral vessel occlusion. Journal of Biomedical Materials Research Part B: Applied Biomaterials, 82(2), 490-499.

Wong, A. Y., Garcia, L. M., & Patel, K. M. (2006). Thrombogenicity assessment of a new generation of peripheral embolization coils. Journal of Biomedical Materials Research Part A, 76(4), 832-841.

Downloads

Published

2024-07-10

How to Cite

Kumar, M. D. P., Mahendralal, K. D. D., Maheshbhai, R. N., Rahul, S., & Jasvantbhai, A. V. (2024). In-Vitro Assessment of Developed Peripheral Fibered Embolization Coil Deployment: A Key to Obstruct Blood Flow in Peripheral Arterial and Venous Vessel. International Journal of Clinical Science and Medical Research, 4(7), 246–252. https://doi.org/10.55677/IJCSMR/V4I7-04/2024