COVID-19 Liver Injury Whether due to Virus or Medication: A Case Report
DOI:
https://doi.org/10.55677/IJCSMR/V2I9-02/2022Keywords:
Coronavirus disease 2019; liver impairment; drug induced liver injury; case reportAbstract
Mild cases of liver injury had been found on COVID-19 cases worldwide. However, the growing prevalence and severity of the cases indicated the dangerous spread of liver impairment to a considerable amount of the population. A 59-year-old COVID positive man come to the emergency room with fever, cough, and nausea. He was treated with favipiravir, azithromycin and other symptomatic drugs. On the seventh day of treatment, patient had a significant increased in liver enzymes, AST was 162 U/L dan ALT was 465 U/L. Patient was diagnosed with acute liver injury. Favipiravir was stopped and he was given hepatoprotection agents. On the tenth day patient had no complaint and was discharged. COVID-19 patients have high risk of impaired liver function, either because of the infection treatment drugs. Administration of hepatoprotective agents and discontinuation of suspected drugs suspected should benefits the patients.
References
Kullar R, Patel AP, Saab S. Hepatic Injury in Patients With COVID-19. J Clin Gastroenterol. 2020. 54:841-849.
Yu D, Du Q, Yan S, Guo XG, He Y, Zhu G, et al. Liver Injury in COVID-19: Clinical Features and Treatment Management. Viral J.2021.18:121
Vitiello A, Porta RL, D’Aiuto V, Ferrara F. The Risks of Liver Injury in COVID-19 Patients and Pharmacological Management to Reduce or Prevent the Damage Induced. Egyp Liv Jour. 2021. 11:11
Ghoda A, Ghoda M. Liver Injury in COVID-19 Infection: A Systematic Review. Cureus. 2020;12(7): e9487.
Wijampreecha K, Ungprasert P, Panjawatanan P, Harnois DM, Zaver HB, Ahmed A, et al. COVID-19 and Liver Injury: a Meta-Analysis. Eur J Gastr and Hep. 2021. 33:990-995.
Sodeifian F, Seyedalhosseini ZS, Kian N, Eftekhari M, Najari S, Mirsaeidi M, et al. Drug-Induced Liver Injury in COVID-19 Patients: A Systematic Review. Front. Med. 2021;8:731436
Sharma V., Samanta J. Dengue and its effects on liver. World J Clin Cases. 2015.3:2