Population Attributable Risk Fraction for Major Cardiovascular Risk Factors for Coronary Artery Disease and Stroke in Palestinians Living in And Out Camps in the Gaza Strip

Authors

  • Amal Jamee Palestinian Ministry of Health, AL-Azhar university, Institute of medical science, Gaza, Palestine
  • Victor Aboyans INSERM, Univ. Limoges, CHU Limoges, IRD, U1094 Tropical Neuroepidemiology, Institute of Epidemiology and Tropical Neurology, GEIST, Limoges, France. & Department of Cardiology, Dupuytren University Hospital, Limoges, France
  • Vanina Bongard UMR 1295 CERPOP, INSERM, UPS, Department of Epidemiology, Health Economics and Public Health, Toulouse University Hospital (CHU), University of Toulouse, 31000 Toulouse, France. & Department of Cardiology, Toulouse University Hospital (CHU), 31000 Toulouse, France.
  • Farid Boumediene INSERM, Univ. Limoges, CHU Limoges, IRD, U1094 Tropical Neuroepidemiology, Institute of Epidemiology and Tropical Neurology, GEIST, Limoges, France.
  • Julien Magn INSERM, Univ. Limoges, CHU Limoges, IRD, U1094 Tropical Neuroepidemiology, Institute of Epidemiology and Tropical Neurology, GEIST, Limoges, France. & Department of Cardiology, Dupuytren University Hospital, Limoges, France
  • Yehia Abed University Al Quods, Gaza, Palestine
  • Pierre-Marie Preux INSERM, Univ. Limoges, CHU Limoges, IRD, U1094 Tropical Neuroepidemiology, Institute of Epidemiology and Tropical Neurology, GEIST, Limoges, France.
  • Philippe Lacroix INSERM, Univ. Limoges, CHU Limoges, IRD, U1094 Tropical Neuroepidemiology, Institute of Epidemiology and Tropical Neurology, GEIST, Limoges, France & Department of Thoracic and Vascular Surgery – Vascular Medicine, Dupuytren University Hospital, Limoges, France

DOI:

https://doi.org/10.55677/IJCSMR/V2I11-02/2022

Keywords:

Population attributable risk fraction; cardiovascular risk factors; Coronary artery disease; Stroke; genders, camp; non-camp; Gaza-Palestine

Abstract

Background: Epidemiological data on cardiovascular diseases in Palestine are scarce. We aimed to estimate the attributable risk of major modifiable cardiovascular risk factors contributing to prevalent coronary artery disease (CAD) and stroke in the Palestinian population in Gaza. More specifically, we compared the population living in and out of camps to assess the potential influence of this specific environmental parameter on cardiovascular epidemiology.

Methods: The prevalence of cardiovascular risk factors and their association with CAD and stroke were studied in a cross-sectional study carried out in the Gazan community among 2240 participants, aged ≥ 25 years. The population attributable risk fractions (PARF) were calculated using an adjusted odds ratio for CAD and stroke. 

Results: The PARF of hypertension, diabetes and low physical activity were respectively at 33.8% (95%CI, 24.8-46.1), 22.3% (95% CI,16.3-30.4) and 16.2% (95% CI,11.9-22.0) for CAD. For stroke, hypertension, diabetes and high level of triglycerides had the highest impact, with PARF reaching 54.4% (95% CI, 32.1-95.1), 39.4% (95%CI,23.9-64.9), and 30.7% (95% CI,18.6-50.6), respectively. Hypertension, diabetes, low PA, and obesity were the factors with the strongest impact on CAD and stroke in women. When comparing the PARF in a population living in camps and those living out of camps, hypertension and diabetes remained the risk factors with the highest PARF for CAD or stroke in persons living in both areas with a slight difference.

Conclusion: A majority of CAD and stroke cases are attributable to major cardiovascular risk factors in the Gazan population. Interventions to reduce cardiovascular disease occurrence should primarily focus on the control of hypertension, diabetes, and obesity as preventable risk factors in this setting.

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Published

2022-11-12

How to Cite

Jamee, A., Victor Aboyans, Vanina Bongard, Farid Boumediene, Julien Magn, Yehia Abed, Pierre-Marie Preux, & Philippe Lacroix. (2022). Population Attributable Risk Fraction for Major Cardiovascular Risk Factors for Coronary Artery Disease and Stroke in Palestinians Living in And Out Camps in the Gaza Strip. International Journal of Clinical Science and Medical Research, 2(11), 90–96. https://doi.org/10.55677/IJCSMR/V2I11-02/2022