Anemia in Diabetic Patients Hospitalized at CHUL

Authors

  • Mfoumou Essono AF Libreville University Hospital Center (Gabon)
  • Mbina E Libreville University Hospital Center (Gabon)
  • Nnang Essone JF Owendo University Hospital Center (Gabon)
  • Kombila D Libreville University Hospital Center (Gabon)
  • Nsame D Libreville University Hospital Center (Gabon)
  • Pambo T Libreville University Hospital Center (Gabon)
  • Igala M Libreville University Hospital Center (Gabon)
  • Boguikouma JB Libreville University Hospital Center (Gabon)

DOI:

https://doi.org/10.55677/IJCSMR/V3I2-03/2023

Keywords:

Anemia, Diabetes, Inflammation, Renal failure

Abstract

Introduction: Anemia is the most common haematological abnormality in diabetics. Understanding the pathogenesis of anemia associated with diabetes can help optimize its management. We conducted a study to determine the biological and etiopathogenic particularities that may be associated with anemia in Gabonese diabetic patients.

Patients and method: Descriptive retrospective study, carried out on the files of diabetic patients hospitalized in the endocrinology department of the Libreville University Hospital during the year 2017. Was included: any hospitalized patient with a hemoglobin ( Hb ) level lower than: 13g/ dl (men), 12g/dl (women). Anemia was mild if Hb in women between 10.9 and 11.9 g/d and in men between 10.9 and 12.9 g/dl Hb , moderate if Hb between 8 and 10.9 g/dl and Severe if Hb >8g/dl. Data analysis: EPI-INFO version 3.5.

Results: 153 records included/782 hospitalizations: prevalence 19.56%. Average age 54.4 years

(±11.1), sex ratio: 1.4 (88 men/65 women). Probable type 2 diabetes (92.20%) Probable type 1 diabetes (6.5%). Average duration of diabetes: 9 years. Mild anemia: 34.6% with mean Hb level 11.98g/dl; moderate: 49% with average Hb level 9.65g/dl and severe 16.3% with average Hb level 6.76g/dl. Hypochromic microcytic anemia (30.7%) hypochromic normocytic (18.3%) normochromic normocytic (27.5%); microcytic normochromia (20.9%) and macrocytic in 2.6% of cases. Etiologically: Probable inflammatory origin (50.3%) Renal failure (24.1%) Iron deficiency (3.4%) etiological factor not found (22.2%). Martial assessment, at the expense of the patients, not carried out (96%).

Conclusion: Anemia is a common biological anomaly in diabetics in Gabon. It is most often moderate, and most often linked to infectious and renal causes.

References

Kabamba Tshikongo Arsene, Kipenge Kyandabike Richie, Mwaba Mulubwa Jean-Jacques et al ; Evaluation of the anemic state of type 2 diabetics, case of the city of Lubumbashi . Medical Tunisia 2015; 93:11

Choukem SP, Fabreguettes C, Akwo E, Porcher R et al. Influence of migration on characteristics of type 2 diabetes in sub-Saharan Africans. Diabetes Metab . 2014 ; 40: 56–60

Cawood TJ, Buckley U, Murray A, Corbett M, Dillon D, Goodwin B, Sreenan S. Prevalence of anemia in patients with diabetes mellitus. Ir J Med Sci. 2006; 175:25–27

Thomas MC, MacIsaac RJ, Tsalamandris C, Molyneaux L, Goubina I, Fulcher G, Yue D, Jerums G. The burden of anemia in type 2 diabetes and the role of nephropathy: a cross-sectional audit. Nephrol Dial Transplant. 2004; 19:1792–7

Ezenwaka CE, Jones- LeCointe A, Nwagbara E, Seales D, Okali F. Anaemia and kidney dysfunction in Caribbean type 2 diabetic patients. Cardiovascular Diabetol . 2008; 7:25.

Angelousi A, Larger E. Anaemia , a common but often unrecognized risk in diabetic patients: a review. Diabetes Metab . 2014;41(1):18–27.

Craig KJ, Williams JD, Riley SG, Smith H, Owens DR, Worthing D, Cavill I, Phillips AO. Anemia and diabetes in the absence of nephropathy. Diabetes Care. 2005; 28:1118–23

Stevens PE, O'Donoghue DJ, Lameire NR. Anaemia in patients with diabetes: unrecognized , undetected and untreated? Curr Med Res Opinion . 2003; 19:395–401.

Kengne AP, Czernichow S, Hamer M, Batty GD, Stamatakis E. Anaemia , haemoglobin level and cause-specific mortality in people with and without diabetes.

0.Friedman EA, L'Esperance FA, Brown CD, Berman DH: Treating azotemia-induced anemia with erythropoietin improves diabetic eye disease. Kidney Int Suppl. 2003;64( Suppl 87):S57–63. Google Scholar

Drüeke TB, Locatelli F, Clyne N, Eckardt KU, Macdougall IC, Tsakiris D, Burger HU, Scherhag A, CREATE Investigators. Normalization of hemoglobin level in patients with chronic kidney disease and anemia. N Engl J Med. 2006; 355: 2071–84.

General Directorate of Statistics, overall results of the 2013 general census of population and housing in Gabon (RGPL-2013), Libreville, 2015, chII page 7.

World Health Organization . Nutritional anemias . Report of a WHO scientific group. World Health Organ Tech Rep Ser. 1968; 405:5–37

Levey AS, Bosch JP, Lewis JB, Greene T, Rogers N, Roth D. A more accurate method to estimate glomerular filtration rate from serum creatinine: a New prediction equation. Ann Intern Med. 1999; 130:461–70.

Monday AP. Quality of life: subjective and objective improvements with recombinant human erythropoietin therapy. Semin Nephrol . 1989; 9(1 Suppl 1):22–9.

Belmahi N, Anoun N, El Ouahabi H, Ajdi F. The particularities of anemia in diabetics, Department of Endocrinology, Diabetology, Metabolic Diseases and Nutrition; CHU Hassan II, Fez. Morocco (poster).

Feteh VF, Choukem SP, Kengne AP, Nebongo DN, Ngowe-Ngowe M. Anemia in type 2 diabetic patients and correlation with kidney function in a tertiary care sub-Saharan African hospital: a cross-sectional study. BMC Nephrol . 2016;17(1):29

Kagu MB, Mshelia DS. Anemia in Patients with Diabetes Mellitus Attending Diabetes Outpatient Clinic in Maiduguri, Nigerian Journal of Health and Biomedical Sciences Vol.4(1) 2005: 1-4.

Hosseini MS, Rostami Z, Saadat A, Saadatmand SM, Naeimi E et al. Anemia and microvascular complications in patients with type 2 diabetes, nephro-urol Mon. 2014; 6 (4): 19976

Amani K, Amani MEA P256 Anemia in diabetics: what particularities? Diabetes & Metabolism . 2009; Vol 35 - No. S1, P. A87.

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Published

2023-02-15

How to Cite

Mfoumou Essono AF, Mbina E, Nnang Essone JF, Kombila D, Nsame D, Pambo T, Igala M, & Boguikouma JB. (2023). Anemia in Diabetic Patients Hospitalized at CHUL. International Journal of Clinical Science and Medical Research, 3(02), 43–47. https://doi.org/10.55677/IJCSMR/V3I2-03/2023