Assessment of Spleen by Ultrasound in Sickle Cell Patient among Indian Population
DOI:
https://doi.org/10.55677/IJCSMR/V3I4-03/2023Keywords:
sickle cell anemia, autosplenectomy, spleen size, ultrasonography, spleen echotexture.Abstract
Background- Ultrasonography is one of the non invasive, cheap, readily available and reliable method for assessment of not only spleen size, but also the echotexture of spleen in cases with sickle cell disease. This study was conducted to sonographically assess and compare the spleen in patients with sickle cell anemia and age and sex matched controls among the Indian population.
Methodology- The study was conducted as an observational comparative study on a total of 80 confirmed cases of Sickle cell anemia and 80 controls at tertiary care centre. Detailed history regarding sociodemographic variables such as age and sex was obtained from all the cases and controls. All the study participants were subjected to ultrasound examination and length, width and echotexture was noted.
Results- A total of 80 cases with sickle cell anemia and matched controls with mean age of 10.59±1.18 years. Mean length as well as width of spleen was found to be significantly higher in cases as compared to controls (p<0.05). Also we noted that all the controls had normal splenic echotexture whereas splenic echotexture was altered in majority of cases with sickle cell disease as described in table 2 (p<0.05).
Conclusion- Splenic abnormalities and complications are common in patients with SCD. While enlarged spleen size is seen in young cases, autosplenectomy, shrunken spleen, infarction, abscess and other changes in echotexture are commonly observed in patients with advancing age. Sonological assessment might help in assessing the splenic complication in patients with SCD and thus must be routinely done in such cases.
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