Primary Anorectal Melanoma: A Case Report

Author's Information:

F. Haddad

Department of Gastroenterology and Proctology, Ibn Rochd University Hospital, Casablanca, Morocco 

A. D. MeliedjeKenmoe

Department of Gastroenterology and Proctology, Ibn Rochd University Hospital, Casablanca, Morocco

Z. Boukhal.

Department of Gastroenterology and Proctology, Ibn Rochd University Hospital, Casablanca, Morocco 

F. Z. Rhaoussi

Department of Gastroenterology and Proctology, Ibn Rochd University Hospital, Casablanca, Morocco

M. Tahiri

Department of Gastroenterology and Proctology, Ibn Rochd University Hospital, Casablanca, Morocco

W. Hliwa

Department of Gastroenterology and Proctology, Ibn Rochd University Hospital, Casablanca, Morocco

A. Bellabah

Department of Gastroenterology and Proctology, Ibn Rochd University Hospital, Casablanca, Morocco

W. Badre

Department of Gastroenterology and Proctology, Ibn Rochd University Hospital, Casablanca, Morocco

Vol 06 No 04 (2026):Volume 06 Issue 04 April 2026

Page No.: 79-80

Abstract:

Malignant anorectalmelanoma is a malignant tumour that developsfrom the pigmentary system. It is a rare tumour,accounting for less than 1% of anorectal cancers and 0.3% of malignant melanomas. Its prognosis is poor due to the early onset of metastases. We report a case.

A 78-year-old female patient with hypertension was admitted for rectal bleeding that had been ongoing for two months, with no other associated symptoms but a deterioration in her general condition. A proctological examination revealed a polypoid tumour with a blackish appearance located 3 cm from the anal margin. Abdominal examination revealed hepatomegaly with a hepatic splenic flexure at 14 cm. Colonoscopy revealed a polyploid mass 2 cm in diameterextending 3 cm in a hemicircular pattern, with a blackish appearance, and scattered nevi on the rectosigmoid mucosa.

Pathological examination of the biopsiesconcluded that the diagnosis was anorectal melanoma, with the presence of anti-PS100 and anti-HMB45 antibodies on immunohistochemistry. Staging investigations revealed liver metastases.

KeyWords:

Rectal bleeding; Anorectal melanoma; Liver metastases

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